Therapeutic Plasma Exchange

An exciting high-level blood filtration technique

Therapeutic Plasma Exchange (TPE), also known as Therapeutic Plasmaphereis has been a powerful tool for treatment of critically-ill patients in hospital settings, for many years. Now the same technology is available to you in an outpatient setting, at Lifespan Health.

TPE is currently being studied for a wide variety of potential benefits, including removal of inflammatory mediators, chemicals, plastics, cellular waste, immune complexes, and other unwanted plasma-based toxins.

Detoxification

Improve health parameters by

decreasing your toxic burden

Lifespan Health is offering this advanced therapy to those who are experiencing chronic inflammation, environmental toxicities, and long-term effects of infectious syndromes--as well as to clients who want to take a proactive approach to wellness and health optimization

The Process

Therapeutic Plasmapheresis is the cornerstone therapy of comprehensive protocols designed to meet your unique health needs and goals.

Each protocol follows a logical, collaborative, diagnostic and treatment framework:

1. ASSESSMENT

Includes a comprehensive medical history review, physical examination, evaluation of blood biomarkers, measurements of toxins. Then we make specific treatment recommendations, assuring that the plan aligns with your expectations.

2. THERAPEUTIC PLASMA EXCHANGE (TPE)

One or more monthly sessions

3. NUTRIENT SUPPORTUtilizing a combination of oral and IV nutrients, specifically designed to augment your TPE procedures, and achieve the very best results.

4. RETEST Compare post-treatment toxin levels and biomarkers with the pre-treatment results.

The Protocols

Each of the Lifespan Health Plasma Exchange protocols are developed by and overseen by Dr. Mark Rawson. The procedure is performed by highly-trained RNs in a comfortable clinic setting.

CHRONIC TOXICITIES

In-person or virtual appointment with Dr. Mark Rawson.
Comprehensive blood biomarkers and toxin level testing
3-5 monthly TPE sessions with supportive IV and oral nutrients and toxin-specific compounds
3 IV ozone therapy sessions (single-pass or EBOO)
6-month supply of ongoing oral support nutrients and toxin-specific compounds
Follow up testing of biomarkers and toxin levels

CHRONIC FATIGUE

In-person or virtual appointment with Dr. Mark Rawson.
Comprehensive blood biomarkers and toxin level testing
3-5 monthly TPE sessions with supportive IV and oral nutrients
Follow up testing of biomarkers
May be incorporated into our chronic fatigue recovery program with additional therapeutic modalities such as hyperbaric oxygen therapy, advanced IV therapy protocols (NAD+, NR, methylene blue,..) and peptide therapies.

HEALTH OPTIMIZATION

In-person or virtual appointment with Dr. Mark Rawson.
Comprehensive blood biomarkers and toxin level testing
3-5 monthly TPE sessions with supportive IV and oral nutrients and toxin-specific compounds
3 IV ozone therapy sessions (single-pass or EBOO)
6-month supply of ongoing oral support nutrients and toxin-specific compounds
Follow up testing of biomarkers and toxin levels

The Procedure

1

2

Blood is removed

After a complete medical evaluation and a detailed explanation of the procedure, you get comfortable in our plasma exhange suite.

In a continuous process, blood is withdrawn...

Blood components
are separated

By a complex centrifuge process, plasma is separated from the other blood components.

The plasma contains numerous toxic substances that will be eliminated from your body.

4

Blood + Replacement
Solution is reinfused

By a complex centrifuge process, plasma is separated from the other blood components.

The plasma contains numerous toxic substances that will be eliminated from your body.

Plasma (with toxins)
is discarded

This plasma is automatically separated into bags, and prepared for disposal.

3

The Science

What does the research and clinican experience reveal about

therapeutic plasma exchange?

Research Studies:

A randomized, controlled clinical trial of plasma exchange with albumin replacement for Alzheimer's disease: Primary results of the AMBAR Study. Boada M, López OL, Olazarán J, et al. Alzheimer's Dement. 2020; 16: 1412–1425. See study...

Plasma Exchange in Alzheimer's Disease. Lucas Rohrer, et al. Transfusion Medicine Reviews 37 (2003) 10-15.

See study...

Can serial therapeutic plasma exchange remove synthetic chemicals from humans? Paul Savage, Paul S. Anderson, et al. Medical Hypotheses 198 (2025) 111630. See study...

Old plasma dilution reduces human biological age: a clinical study. Daehwan Kim, et al. GeroScience (2022) 44:2701-2720. See study...

In the Media:

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Videos:

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Questions & Answers

Is Plasma Exchange covered by insurance?

Unfortunately, plasma exchange procedures are not covered by most health insurance carriers. We are happy to provide you with a superbill to submit for reimbursement, if you would like to try.

Does Lifespan offer financing for TPE procedures and packages?

Yes, we offer financing options: 1. You may pay 50% of the cost initially, and then the remaining balance over a 90-day period. 2. You may utilize one of our 3rd-party financing partner programs.

Are Plasma Exchange, Plasmapheresis and Apheressis the same thing?

While all three involve removing and separating blood, there are key differences: Aphersis refers to procedure where blood is removed and separated into components, with one or more components removed. Plasmapheresi refers to small volume plasma removal, without returning replacement fluid (e.g. plasma donation) Plasma Exchange refers to the large volume plasma removal, followed by replacement of of a fresh plasma substitue fluid (albumin + saline).

How long does a plasma exchange treatment take?

The plasma exchange treatment itself takes about 90 minutes. However, allow for 3-4 hours to accomadate intake activity, vascular access and post-treatment observation.